Hi,
If you are in Madrid for a short time and would like to go on a day-trip I would recommend either Toledo or Segovia. These are like living museums and are a lot closer to Madrid than Sevilla or Granada. You may suffer from overkill if you try to visit all 3 museums you mentioned - there's enough to see in one museum to keep you enthralled for one holiday. Of course you should see the Plaza Mayor; the Puerta del Sol is somewhere you're bound to come across at some stage.
Anyway, I hope you have a marvellous time
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An English Bookseller in Madrid